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Lercigan Brand names, Lercigan Analogs

Lercigan Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Lercigan Chemical_Formula


Lercigan RX_link


Lercigan fda sheet

Lercigan FDA

Lercigan msds (material safety sheet)

Lercigan Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Lercigan Molecular Weight

284.42 g/mol

Lercigan Melting Point


Lercigan H2O Solubility

Freely soluble

Lercigan State


Lercigan LogP


Lercigan Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Lercigan Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Lercigan Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Lercigan Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Lercigan side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Lercigan Patient Information

Lercigan Organisms Affected

Humans and other mammals