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Iergigan Brand names, Iergigan Analogs

Iergigan Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Iergigan Chemical_Formula


Iergigan RX_link

Iergigan fda sheet

Iergigan FDA

Iergigan msds (material safety sheet)

Iergigan Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Iergigan Molecular Weight

284.42 g/mol

Iergigan Melting Point


Iergigan H2O Solubility

Freely soluble

Iergigan State


Iergigan LogP


Iergigan Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Iergigan Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Iergigan Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Iergigan Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Iergigan side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Iergigan Patient Information

Iergigan Organisms Affected

Humans and other mammals