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Fenetazina Brand names, Fenetazina Analogs

Fenetazina Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Fenetazina Chemical_Formula


Fenetazina RX_link


Fenetazina fda sheet

Fenetazina FDA

Fenetazina msds (material safety sheet)

Fenetazina Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Fenetazina Molecular Weight

284.42 g/mol

Fenetazina Melting Point


Fenetazina H2O Solubility

Freely soluble

Fenetazina State


Fenetazina LogP


Fenetazina Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Fenetazina Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Fenetazina Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Fenetazina Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Fenetazina side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Fenetazina Patient Information

Fenetazina Organisms Affected

Humans and other mammals