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Prometh Fortis Brand names, Prometh Fortis Analogs

Prometh Fortis Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Prometh Fortis Chemical_Formula

C17H20N2S

Prometh Fortis RX_link

http://www.rxlist.com/cgi/generic3/phenergan.htm

Prometh Fortis fda sheet

Prometh_Fortis FDA

Prometh Fortis msds (material safety sheet)

Prometh Fortis Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Prometh Fortis Molecular Weight

284.42 g/mol

Prometh Fortis Melting Point

60oC

Prometh Fortis H2O Solubility

Freely soluble

Prometh Fortis State

Solid

Prometh Fortis LogP

4.946

Prometh Fortis Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Prometh Fortis Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Prometh Fortis Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Prometh Fortis Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Prometh Fortis side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Prometh Fortis Patient Information

Prometh Fortis Organisms Affected

Humans and other mammals