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Pyrethia Brand names, Pyrethia Analogs

Pyrethia Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Pyrethia Chemical_Formula


Pyrethia RX_link

Pyrethia fda sheet

Pyrethia FDA

Pyrethia msds (material safety sheet)

Pyrethia Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Pyrethia Molecular Weight

284.42 g/mol

Pyrethia Melting Point


Pyrethia H2O Solubility

Freely soluble

Pyrethia State


Pyrethia LogP


Pyrethia Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Pyrethia Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Pyrethia Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Pyrethia Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Pyrethia side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Pyrethia Patient Information

Pyrethia Organisms Affected

Humans and other mammals