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Procit Brand names, Procit Analogs

Procit Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Procit Chemical_Formula


Procit RX_link

Procit fda sheet

Procit FDA

Procit msds (material safety sheet)

Procit Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Procit Molecular Weight

284.42 g/mol

Procit Melting Point


Procit H2O Solubility

Freely soluble

Procit State


Procit LogP


Procit Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Procit Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Procit Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Procit Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Procit side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Procit Patient Information

Procit Organisms Affected

Humans and other mammals