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Remsed Brand names, Remsed Analogs

Remsed Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Remsed Chemical_Formula


Remsed RX_link

Remsed fda sheet

Remsed FDA

Remsed msds (material safety sheet)

Remsed Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Remsed Molecular Weight

284.42 g/mol

Remsed Melting Point


Remsed H2O Solubility

Freely soluble

Remsed State


Remsed LogP


Remsed Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Remsed Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Remsed Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Remsed Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Remsed side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Remsed Patient Information

Remsed Organisms Affected

Humans and other mammals