Promethazine Hcl
Promethazine Hcl Brand names, Promethazine Hcl Analogs
- Allergan
- Aprobit
- Atosil
- Avomine
- Dimapp
- Diphergan
- Diprazine
- Diprozin
- Dorme
- Duplamin
- Fargan
- Fellozine
- Fenazil
- Fenergan
- Fenetazina
- Genphen
- Hiberna
- Histargan
- Iergigan
- Isophenergan
- Isopromethazine
- Lercigan
- Lergigan
- Lilly 1516
- Mymethazine Fortis
- Phargan
- Phenargan
- Phencen
- Phenergan
- Phenergan Fortis
- Phensedyl
- Pilpophen
- Pipolphen
- Proazaimine
- Proazamine
- Procit
- Promazinamide
- Prometasin
- Prometazin
- Prometh Fortis
- Prometh Plain
- Promethacon
- Promethaine
- Promethazin
- Promethazine Hcl
- Promethazine Plain
- Promethegan
- Promethiazine
- Promezathine
- Prorex
- Protazine
- Prothazin
- Prothazine
- Provigan
- Pyrethia
- Pyrethiazine
- Remsed
- Romergan
- Synalgos
- Tanidil
- Thiergan
- Valergine
- Vallergine
- Zipan-25
Promethazine Hcl Brand Names Mixture
- Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)
Promethazine Hcl Chemical_Formula
C17H20N2S
Promethazine Hcl RX_link
http://www.rxlist.com/cgi/generic3/phenergan.htm
Promethazine Hcl fda sheet
Promethazine Hcl msds (material safety sheet)
Promethazine Hcl Synthesis Reference
Charpentier, U.S. Pat. 2,503,451 (1950)
Promethazine Hcl Molecular Weight
284.42 g/mol
Promethazine Hcl Melting Point
60oC
Promethazine Hcl H2O Solubility
Freely soluble
Promethazine Hcl State
Solid
Promethazine Hcl LogP
4.946
Promethazine Hcl Dosage Forms
Tablet; Suppository; Opthalmic drops; Syrup
Promethazine Hcl Indication
For the treatment of allergic disorders, itching, nausea and vomiting.
Promethazine Hcl Pharmacology
Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.
Promethazine Hcl Absorption
On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.
Promethazine Hcl side effects and Toxicity
Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)
Promethazine Hcl Patient Information
Promethazine Hcl Organisms Affected
Humans and other mammals
