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Prorex Brand names, Prorex Analogs

Prorex Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Prorex Chemical_Formula


Prorex RX_link

Prorex fda sheet

Prorex FDA

Prorex msds (material safety sheet)

Prorex Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Prorex Molecular Weight

284.42 g/mol

Prorex Melting Point


Prorex H2O Solubility

Freely soluble

Prorex State


Prorex LogP


Prorex Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Prorex Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Prorex Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Prorex Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Prorex side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Prorex Patient Information

Prorex Organisms Affected

Humans and other mammals