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Tanidil Brand names, Tanidil Analogs

Tanidil Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Tanidil Chemical_Formula

C17H20N2S

Tanidil RX_link

http://www.rxlist.com/cgi/generic3/phenergan.htm

Tanidil fda sheet

Tanidil FDA

Tanidil msds (material safety sheet)

Tanidil Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Tanidil Molecular Weight

284.42 g/mol

Tanidil Melting Point

60oC

Tanidil H2O Solubility

Freely soluble

Tanidil State

Solid

Tanidil LogP

4.946

Tanidil Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Tanidil Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Tanidil Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Tanidil Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Tanidil side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Tanidil Patient Information

Tanidil Organisms Affected

Humans and other mammals