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Diprozin Brand names, Diprozin Analogs

Diprozin Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Diprozin Chemical_Formula


Diprozin RX_link


Diprozin fda sheet

Diprozin FDA

Diprozin msds (material safety sheet)

Diprozin Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Diprozin Molecular Weight

284.42 g/mol

Diprozin Melting Point


Diprozin H2O Solubility

Freely soluble

Diprozin State


Diprozin LogP


Diprozin Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Diprozin Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Diprozin Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Diprozin Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Diprozin side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Diprozin Patient Information

Diprozin Organisms Affected

Humans and other mammals