o-Methoxyphenyl glyceryl ether
Brand names,
o-Methoxyphenyl glyceryl ether
Analogs
o-Methoxyphenyl glyceryl ether
Brand Names Mixture
o-Methoxyphenyl glyceryl ether
Chemical_Formula
C10H14O4
o-Methoxyphenyl glyceryl ether
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
o-Methoxyphenyl glyceryl ether
fda sheet
o-Methoxyphenyl glyceryl ether
msds (material safety sheet)
o-Methoxyphenyl glyceryl ether
Synthesis Reference
No information avaliable
o-Methoxyphenyl glyceryl ether
Molecular Weight
198.216 g/mol
o-Methoxyphenyl glyceryl ether
Melting Point
78.5 oC
o-Methoxyphenyl glyceryl ether
H2O Solubility
50 mg/mL
o-Methoxyphenyl glyceryl ether
State
Solid
o-Methoxyphenyl glyceryl ether
LogP
0.95
o-Methoxyphenyl glyceryl ether
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
o-Methoxyphenyl glyceryl ether
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
o-Methoxyphenyl glyceryl ether
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
o-Methoxyphenyl glyceryl ether
Absorption
Rapidly absorbed from the GI tract
o-Methoxyphenyl glyceryl ether
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
o-Methoxyphenyl glyceryl ether
Patient Information
No information avaliable
o-Methoxyphenyl glyceryl ether
Organisms Affected
Humans and other mammals