Tenntus
Brand names,
Tenntus
Analogs
Tenntus
Brand Names Mixture
Tenntus
Chemical_Formula
C10H14O4
Tenntus
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Tenntus
fda sheet
Tenntus
msds (material safety sheet)
Tenntus
Synthesis Reference
No information avaliable
Tenntus
Molecular Weight
198.216 g/mol
Tenntus
Melting Point
78.5 oC
Tenntus
H2O Solubility
50 mg/mL
Tenntus
State
Solid
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LogP
0.95
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Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Tenntus
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Tenntus
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Tenntus
Absorption
Rapidly absorbed from the GI tract
Tenntus
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Tenntus
Patient Information
No information avaliable
Tenntus
Organisms Affected
Humans and other mammals