Sirotol
Brand names,
Sirotol
Analogs
Sirotol
Brand Names Mixture
Sirotol
Chemical_Formula
C10H14O4
Sirotol
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Sirotol
fda sheet
Sirotol
msds (material safety sheet)
Sirotol
Synthesis Reference
No information avaliable
Sirotol
Molecular Weight
198.216 g/mol
Sirotol
Melting Point
78.5 oC
Sirotol
H2O Solubility
50 mg/mL
Sirotol
State
Solid
Sirotol
LogP
0.95
Sirotol
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Sirotol
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Sirotol
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Sirotol
Absorption
Rapidly absorbed from the GI tract
Sirotol
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Sirotol
Patient Information
No information avaliable
Sirotol
Organisms Affected
Humans and other mammals