Amonidren
Brand names,
Amonidren
Analogs
Amonidren
Brand Names Mixture
Amonidren
Chemical_Formula
C10H14O4
Amonidren
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Amonidren
fda sheet
Amonidren
msds (material safety sheet)
Amonidren
Synthesis Reference
No information avaliable
Amonidren
Molecular Weight
198.216 g/mol
Amonidren
Melting Point
78.5 oC
Amonidren
H2O Solubility
50 mg/mL
Amonidren
State
Solid
Amonidren
LogP
0.95
Amonidren
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Amonidren
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Amonidren
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Amonidren
Absorption
Rapidly absorbed from the GI tract
Amonidren
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Amonidren
Patient Information
No information avaliable
Amonidren
Organisms Affected
Humans and other mammals