Guanar
Brand names,
Guanar
Analogs
Guanar
Brand Names Mixture
Guanar
Chemical_Formula
C10H14O4
Guanar
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guanar
fda sheet
Guanar
msds (material safety sheet)
Guanar
Synthesis Reference
No information avaliable
Guanar
Molecular Weight
198.216 g/mol
Guanar
Melting Point
78.5 oC
Guanar
H2O Solubility
50 mg/mL
Guanar
State
Solid
Guanar
LogP
0.95
Guanar
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guanar
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guanar
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guanar
Absorption
Rapidly absorbed from the GI tract
Guanar
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guanar
Patient Information
No information avaliable
Guanar
Organisms Affected
Humans and other mammals