Breonesin
Brand names,
Breonesin
Analogs
Breonesin
Brand Names Mixture
Breonesin
Chemical_Formula
C10H14O4
Breonesin
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Breonesin
fda sheet
Breonesin
msds (material safety sheet)
Breonesin
Synthesis Reference
No information avaliable
Breonesin
Molecular Weight
198.216 g/mol
Breonesin
Melting Point
78.5 oC
Breonesin
H2O Solubility
50 mg/mL
Breonesin
State
Solid
Breonesin
LogP
0.95
Breonesin
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Breonesin
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Breonesin
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Breonesin
Absorption
Rapidly absorbed from the GI tract
Breonesin
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Breonesin
Patient Information
No information avaliable
Breonesin
Organisms Affected
Humans and other mammals