Calmipan
Brand names,
Calmipan
Analogs
Calmipan
Brand Names Mixture
Calmipan
Chemical_Formula
C10H14O4
Calmipan
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Calmipan
fda sheet
Calmipan
msds (material safety sheet)
Calmipan
Synthesis Reference
No information avaliable
Calmipan
Molecular Weight
198.216 g/mol
Calmipan
Melting Point
78.5 oC
Calmipan
H2O Solubility
50 mg/mL
Calmipan
State
Solid
Calmipan
LogP
0.95
Calmipan
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Calmipan
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Calmipan
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Calmipan
Absorption
Rapidly absorbed from the GI tract
Calmipan
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Calmipan
Patient Information
No information avaliable
Calmipan
Organisms Affected
Humans and other mammals