Neurotone
Brand names,
Neurotone
Analogs
Neurotone
Brand Names Mixture
Neurotone
Chemical_Formula
C10H14O4
Neurotone
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Neurotone
fda sheet
Neurotone
msds (material safety sheet)
Neurotone
Synthesis Reference
No information avaliable
Neurotone
Molecular Weight
198.216 g/mol
Neurotone
Melting Point
78.5 oC
Neurotone
H2O Solubility
50 mg/mL
Neurotone
State
Solid
Neurotone
LogP
0.95
Neurotone
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Neurotone
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Neurotone
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Neurotone
Absorption
Rapidly absorbed from the GI tract
Neurotone
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Neurotone
Patient Information
No information avaliable
Neurotone
Organisms Affected
Humans and other mammals