Glyceryl guaiacolate ether
Brand names,
Glyceryl guaiacolate ether
Analogs
Glyceryl guaiacolate ether
Brand Names Mixture
Glyceryl guaiacolate ether
Chemical_Formula
C10H14O4
Glyceryl guaiacolate ether
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Glyceryl guaiacolate ether
fda sheet
Glyceryl guaiacolate ether
msds (material safety sheet)
Glyceryl guaiacolate ether
Synthesis Reference
No information avaliable
Glyceryl guaiacolate ether
Molecular Weight
198.216 g/mol
Glyceryl guaiacolate ether
Melting Point
78.5 oC
Glyceryl guaiacolate ether
H2O Solubility
50 mg/mL
Glyceryl guaiacolate ether
State
Solid
Glyceryl guaiacolate ether
LogP
0.95
Glyceryl guaiacolate ether
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Glyceryl guaiacolate ether
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Glyceryl guaiacolate ether
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Glyceryl guaiacolate ether
Absorption
Rapidly absorbed from the GI tract
Glyceryl guaiacolate ether
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Glyceryl guaiacolate ether
Patient Information
No information avaliable
Glyceryl guaiacolate ether
Organisms Affected
Humans and other mammals