Colrex expectorant
Brand names,
Colrex expectorant
Analogs
Colrex expectorant
Brand Names Mixture
Colrex expectorant
Chemical_Formula
C10H14O4
Colrex expectorant
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Colrex expectorant
fda sheet
Colrex expectorant
msds (material safety sheet)
Colrex expectorant
Synthesis Reference
No information avaliable
Colrex expectorant
Molecular Weight
198.216 g/mol
Colrex expectorant
Melting Point
78.5 oC
Colrex expectorant
H2O Solubility
50 mg/mL
Colrex expectorant
State
Solid
Colrex expectorant
LogP
0.95
Colrex expectorant
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Colrex expectorant
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Colrex expectorant
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Colrex expectorant
Absorption
Rapidly absorbed from the GI tract
Colrex expectorant
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Colrex expectorant
Patient Information
No information avaliable
Colrex expectorant
Organisms Affected
Humans and other mammals