Gnaifenesin
Brand names,
Gnaifenesin
Analogs
Gnaifenesin
Brand Names Mixture
Gnaifenesin
Chemical_Formula
C10H14O4
Gnaifenesin
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Gnaifenesin
fda sheet
Gnaifenesin
msds (material safety sheet)
Gnaifenesin
Synthesis Reference
No information avaliable
Gnaifenesin
Molecular Weight
198.216 g/mol
Gnaifenesin
Melting Point
78.5 oC
Gnaifenesin
H2O Solubility
50 mg/mL
Gnaifenesin
State
Solid
Gnaifenesin
LogP
0.95
Gnaifenesin
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Gnaifenesin
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Gnaifenesin
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Gnaifenesin
Absorption
Rapidly absorbed from the GI tract
Gnaifenesin
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Gnaifenesin
Patient Information
No information avaliable
Gnaifenesin
Organisms Affected
Humans and other mammals