Cortussin
Brand names,
Cortussin
Analogs
Cortussin
Brand Names Mixture
Cortussin
Chemical_Formula
C10H14O4
Cortussin
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Cortussin
fda sheet
Cortussin
msds (material safety sheet)
Cortussin
Synthesis Reference
No information avaliable
Cortussin
Molecular Weight
198.216 g/mol
Cortussin
Melting Point
78.5 oC
Cortussin
H2O Solubility
50 mg/mL
Cortussin
State
Solid
Cortussin
LogP
0.95
Cortussin
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Cortussin
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Cortussin
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Cortussin
Absorption
Rapidly absorbed from the GI tract
Cortussin
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Cortussin
Patient Information
No information avaliable
Cortussin
Organisms Affected
Humans and other mammals