Guaiacurane
Brand names,
Guaiacurane
Analogs
Guaiacurane
Brand Names Mixture
Guaiacurane
Chemical_Formula
C10H14O4
Guaiacurane
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaiacurane
fda sheet
Guaiacurane
msds (material safety sheet)
Guaiacurane
Synthesis Reference
No information avaliable
Guaiacurane
Molecular Weight
198.216 g/mol
Guaiacurane
Melting Point
78.5 oC
Guaiacurane
H2O Solubility
50 mg/mL
Guaiacurane
State
Solid
Guaiacurane
LogP
0.95
Guaiacurane
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaiacurane
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaiacurane
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaiacurane
Absorption
Rapidly absorbed from the GI tract
Guaiacurane
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guaiacurane
Patient Information
No information avaliable
Guaiacurane
Organisms Affected
Humans and other mammals