Glycerol guaiacolate
Brand names,
Glycerol guaiacolate
Analogs
Glycerol guaiacolate
Brand Names Mixture
Glycerol guaiacolate
Chemical_Formula
C10H14O4
Glycerol guaiacolate
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Glycerol guaiacolate
fda sheet
Glycerol guaiacolate
msds (material safety sheet)
Glycerol guaiacolate
Synthesis Reference
No information avaliable
Glycerol guaiacolate
Molecular Weight
198.216 g/mol
Glycerol guaiacolate
Melting Point
78.5 oC
Glycerol guaiacolate
H2O Solubility
50 mg/mL
Glycerol guaiacolate
State
Solid
Glycerol guaiacolate
LogP
0.95
Glycerol guaiacolate
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Glycerol guaiacolate
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Glycerol guaiacolate
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Glycerol guaiacolate
Absorption
Rapidly absorbed from the GI tract
Glycerol guaiacolate
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Glycerol guaiacolate
Patient Information
No information avaliable
Glycerol guaiacolate
Organisms Affected
Humans and other mammals