Guaicol glyceryl ether
Brand names,
Guaicol glyceryl ether
Analogs
Guaicol glyceryl ether
Brand Names Mixture
Guaicol glyceryl ether
Chemical_Formula
C10H14O4
Guaicol glyceryl ether
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaicol glyceryl ether
fda sheet
Guaicol glyceryl ether
msds (material safety sheet)
Guaicol glyceryl ether
Synthesis Reference
No information avaliable
Guaicol glyceryl ether
Molecular Weight
198.216 g/mol
Guaicol glyceryl ether
Melting Point
78.5 oC
Guaicol glyceryl ether
H2O Solubility
50 mg/mL
Guaicol glyceryl ether
State
Solid
Guaicol glyceryl ether
LogP
0.95
Guaicol glyceryl ether
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaicol glyceryl ether
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaicol glyceryl ether
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaicol glyceryl ether
Absorption
Rapidly absorbed from the GI tract
Guaicol glyceryl ether
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guaicol glyceryl ether
Patient Information
No information avaliable
Guaicol glyceryl ether
Organisms Affected
Humans and other mammals