Guiatuss
Brand names,
Guiatuss
Analogs
Guiatuss
Brand Names Mixture
Guiatuss
Chemical_Formula
C10H14O4
Guiatuss
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guiatuss
fda sheet
Guiatuss
msds (material safety sheet)
Guiatuss
Synthesis Reference
No information avaliable
Guiatuss
Molecular Weight
198.216 g/mol
Guiatuss
Melting Point
78.5 oC
Guiatuss
H2O Solubility
50 mg/mL
Guiatuss
State
Solid
Guiatuss
LogP
0.95
Guiatuss
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guiatuss
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guiatuss
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guiatuss
Absorption
Rapidly absorbed from the GI tract
Guiatuss
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guiatuss
Patient Information
No information avaliable
Guiatuss
Organisms Affected
Humans and other mammals