Guaiphesin
Brand names,
Guaiphesin
Analogs
Guaiphesin
Brand Names Mixture
Guaiphesin
Chemical_Formula
C10H14O4
Guaiphesin
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaiphesin
fda sheet
Guaiphesin
msds (material safety sheet)
Guaiphesin
Synthesis Reference
No information avaliable
Guaiphesin
Molecular Weight
198.216 g/mol
Guaiphesin
Melting Point
78.5 oC
Guaiphesin
H2O Solubility
50 mg/mL
Guaiphesin
State
Solid
Guaiphesin
LogP
0.95
Guaiphesin
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaiphesin
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaiphesin
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaiphesin
Absorption
Rapidly absorbed from the GI tract
Guaiphesin
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guaiphesin
Patient Information
No information avaliable
Guaiphesin
Organisms Affected
Humans and other mammals