Guaianesin
Brand names,
Guaianesin
Analogs
Guaianesin
Brand Names Mixture
Guaianesin
Chemical_Formula
C10H14O4
Guaianesin
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaianesin
fda sheet
Guaianesin
msds (material safety sheet)
Guaianesin
Synthesis Reference
No information avaliable
Guaianesin
Molecular Weight
198.216 g/mol
Guaianesin
Melting Point
78.5 oC
Guaianesin
H2O Solubility
50 mg/mL
Guaianesin
State
Solid
Guaianesin
LogP
0.95
Guaianesin
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaianesin
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaianesin
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaianesin
Absorption
Rapidly absorbed from the GI tract
Guaianesin
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guaianesin
Patient Information
No information avaliable
Guaianesin
Organisms Affected
Humans and other mammals