Metfenossidiolo
Brand names,
Metfenossidiolo
Analogs
Metfenossidiolo
Brand Names Mixture
Metfenossidiolo
Chemical_Formula
C10H14O4
Metfenossidiolo
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Metfenossidiolo
fda sheet
Metfenossidiolo
msds (material safety sheet)
Metfenossidiolo
Synthesis Reference
No information avaliable
Metfenossidiolo
Molecular Weight
198.216 g/mol
Metfenossidiolo
Melting Point
78.5 oC
Metfenossidiolo
H2O Solubility
50 mg/mL
Metfenossidiolo
State
Solid
Metfenossidiolo
LogP
0.95
Metfenossidiolo
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Metfenossidiolo
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Metfenossidiolo
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Metfenossidiolo
Absorption
Rapidly absorbed from the GI tract
Metfenossidiolo
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Metfenossidiolo
Patient Information
No information avaliable
Metfenossidiolo
Organisms Affected
Humans and other mammals