Methoxypropanediol
Brand names,
Methoxypropanediol
Analogs
Methoxypropanediol
Brand Names Mixture
Methoxypropanediol
Chemical_Formula
C10H14O4
Methoxypropanediol
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Methoxypropanediol
fda sheet
Methoxypropanediol
msds (material safety sheet)
Methoxypropanediol
Synthesis Reference
No information avaliable
Methoxypropanediol
Molecular Weight
198.216 g/mol
Methoxypropanediol
Melting Point
78.5 oC
Methoxypropanediol
H2O Solubility
50 mg/mL
Methoxypropanediol
State
Solid
Methoxypropanediol
LogP
0.95
Methoxypropanediol
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Methoxypropanediol
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Methoxypropanediol
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Methoxypropanediol
Absorption
Rapidly absorbed from the GI tract
Methoxypropanediol
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Methoxypropanediol
Patient Information
No information avaliable
Methoxypropanediol
Organisms Affected
Humans and other mammals