Dorassin
Brand names,
Dorassin
Analogs
Dorassin
Brand Names Mixture
Dorassin
Chemical_Formula
C10H14O4
Dorassin
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Dorassin
fda sheet
Dorassin
msds (material safety sheet)
Dorassin
Synthesis Reference
No information avaliable
Dorassin
Molecular Weight
198.216 g/mol
Dorassin
Melting Point
78.5 oC
Dorassin
H2O Solubility
50 mg/mL
Dorassin
State
Solid
Dorassin
LogP
0.95
Dorassin
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Dorassin
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Dorassin
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Dorassin
Absorption
Rapidly absorbed from the GI tract
Dorassin
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Dorassin
Patient Information
No information avaliable
Dorassin
Organisms Affected
Humans and other mammals