Tolseron
Brand names,
Tolseron
Analogs
Tolseron
Brand Names Mixture
Tolseron
Chemical_Formula
C10H14O4
Tolseron
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Tolseron
fda sheet
Tolseron
msds (material safety sheet)
Tolseron
Synthesis Reference
No information avaliable
Tolseron
Molecular Weight
198.216 g/mol
Tolseron
Melting Point
78.5 oC
Tolseron
H2O Solubility
50 mg/mL
Tolseron
State
Solid
Tolseron
LogP
0.95
Tolseron
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Tolseron
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Tolseron
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Tolseron
Absorption
Rapidly absorbed from the GI tract
Tolseron
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Tolseron
Patient Information
No information avaliable
Tolseron
Organisms Affected
Humans and other mammals