Calmylin Expectorant
Brand names,
Calmylin Expectorant
Analogs
Calmylin Expectorant
Brand Names Mixture
Calmylin Expectorant
Chemical_Formula
C10H14O4
Calmylin Expectorant
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Calmylin Expectorant
fda sheet
Calmylin Expectorant
msds (material safety sheet)
Calmylin Expectorant
Synthesis Reference
No information avaliable
Calmylin Expectorant
Molecular Weight
198.216 g/mol
Calmylin Expectorant
Melting Point
78.5 oC
Calmylin Expectorant
H2O Solubility
50 mg/mL
Calmylin Expectorant
State
Solid
Calmylin Expectorant
LogP
0.95
Calmylin Expectorant
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Calmylin Expectorant
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Calmylin Expectorant
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Calmylin Expectorant
Absorption
Rapidly absorbed from the GI tract
Calmylin Expectorant
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Calmylin Expectorant
Patient Information
No information avaliable
Calmylin Expectorant
Organisms Affected
Humans and other mammals