Gvaja
Brand names,
Gvaja
Analogs
Gvaja
Brand Names Mixture
Gvaja
Chemical_Formula
C10H14O4
Gvaja
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Gvaja
fda sheet
Gvaja
msds (material safety sheet)
Gvaja
Synthesis Reference
No information avaliable
Gvaja
Molecular Weight
198.216 g/mol
Gvaja
Melting Point
78.5 oC
Gvaja
H2O Solubility
50 mg/mL
Gvaja
State
Solid
Gvaja
LogP
0.95
Gvaja
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Gvaja
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Gvaja
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Gvaja
Absorption
Rapidly absorbed from the GI tract
Gvaja
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Gvaja
Patient Information
No information avaliable
Gvaja
Organisms Affected
Humans and other mammals