Tenntuss
Brand names,
Tenntuss
Analogs
Tenntuss
Brand Names Mixture
Tenntuss
Chemical_Formula
C10H14O4
Tenntuss
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Tenntuss
fda sheet
Tenntuss
msds (material safety sheet)
Tenntuss
Synthesis Reference
No information avaliable
Tenntuss
Molecular Weight
198.216 g/mol
Tenntuss
Melting Point
78.5 oC
Tenntuss
H2O Solubility
50 mg/mL
Tenntuss
State
Solid
Tenntuss
LogP
0.95
Tenntuss
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Tenntuss
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Tenntuss
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Tenntuss
Absorption
Rapidly absorbed from the GI tract
Tenntuss
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Tenntuss
Patient Information
No information avaliable
Tenntuss
Organisms Affected
Humans and other mammals