Propanosedyl
Brand names,
Propanosedyl
Analogs
Propanosedyl
Brand Names Mixture
Propanosedyl
Chemical_Formula
C10H14O4
Propanosedyl
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Propanosedyl
fda sheet
Propanosedyl
msds (material safety sheet)
Propanosedyl
Synthesis Reference
No information avaliable
Propanosedyl
Molecular Weight
198.216 g/mol
Propanosedyl
Melting Point
78.5 oC
Propanosedyl
H2O Solubility
50 mg/mL
Propanosedyl
State
Solid
Propanosedyl
LogP
0.95
Propanosedyl
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Propanosedyl
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Propanosedyl
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Propanosedyl
Absorption
Rapidly absorbed from the GI tract
Propanosedyl
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Propanosedyl
Patient Information
No information avaliable
Propanosedyl
Organisms Affected
Humans and other mammals