Guajacol-glycerinaether
Brand names,
Guajacol-glycerinaether
Analogs
Guajacol-glycerinaether
Brand Names Mixture
Guajacol-glycerinaether
Chemical_Formula
C10H14O4
Guajacol-glycerinaether
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guajacol-glycerinaether
fda sheet
Guajacol-glycerinaether
msds (material safety sheet)
Guajacol-glycerinaether
Synthesis Reference
No information avaliable
Guajacol-glycerinaether
Molecular Weight
198.216 g/mol
Guajacol-glycerinaether
Melting Point
78.5 oC
Guajacol-glycerinaether
H2O Solubility
50 mg/mL
Guajacol-glycerinaether
State
Solid
Guajacol-glycerinaether
LogP
0.95
Guajacol-glycerinaether
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guajacol-glycerinaether
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guajacol-glycerinaether
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guajacol-glycerinaether
Absorption
Rapidly absorbed from the GI tract
Guajacol-glycerinaether
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guajacol-glycerinaether
Patient Information
No information avaliable
Guajacol-glycerinaether
Organisms Affected
Humans and other mammals