Guajamar
Brand names,
Guajamar
Analogs
Guajamar
Brand Names Mixture
Guajamar
Chemical_Formula
C10H14O4
Guajamar
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guajamar
fda sheet
Guajamar
msds (material safety sheet)
Guajamar
Synthesis Reference
No information avaliable
Guajamar
Molecular Weight
198.216 g/mol
Guajamar
Melting Point
78.5 oC
Guajamar
H2O Solubility
50 mg/mL
Guajamar
State
Solid
Guajamar
LogP
0.95
Guajamar
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guajamar
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guajamar
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guajamar
Absorption
Rapidly absorbed from the GI tract
Guajamar
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guajamar
Patient Information
No information avaliable
Guajamar
Organisms Affected
Humans and other mammals