Guiaphenesin
Brand names,
Guiaphenesin
Analogs
Guiaphenesin
Brand Names Mixture
Guiaphenesin
Chemical_Formula
C10H14O4
Guiaphenesin
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guiaphenesin
fda sheet
Guiaphenesin
msds (material safety sheet)
Guiaphenesin
Synthesis Reference
No information avaliable
Guiaphenesin
Molecular Weight
198.216 g/mol
Guiaphenesin
Melting Point
78.5 oC
Guiaphenesin
H2O Solubility
50 mg/mL
Guiaphenesin
State
Solid
Guiaphenesin
LogP
0.95
Guiaphenesin
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guiaphenesin
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guiaphenesin
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guiaphenesin
Absorption
Rapidly absorbed from the GI tract
Guiaphenesin
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guiaphenesin
Patient Information
No information avaliable
Guiaphenesin
Organisms Affected
Humans and other mammals