Mucostop
Brand names,
Mucostop
Analogs
Mucostop
Brand Names Mixture
Mucostop
Chemical_Formula
C10H14O4
Mucostop
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Mucostop
fda sheet
Mucostop
msds (material safety sheet)
Mucostop
Synthesis Reference
No information avaliable
Mucostop
Molecular Weight
198.216 g/mol
Mucostop
Melting Point
78.5 oC
Mucostop
H2O Solubility
50 mg/mL
Mucostop
State
Solid
Mucostop
LogP
0.95
Mucostop
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Mucostop
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Mucostop
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Mucostop
Absorption
Rapidly absorbed from the GI tract
Mucostop
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Mucostop
Patient Information
No information avaliable
Mucostop
Organisms Affected
Humans and other mammals