Oresol
Brand names,
Oresol
Analogs
Oresol
Brand Names Mixture
Oresol
Chemical_Formula
C10H14O4
Oresol
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Oresol
fda sheet
Oresol
msds (material safety sheet)
Oresol
Synthesis Reference
No information avaliable
Oresol
Molecular Weight
198.216 g/mol
Oresol
Melting Point
78.5 oC
Oresol
H2O Solubility
50 mg/mL
Oresol
State
Solid
Oresol
LogP
0.95
Oresol
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Oresol
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Oresol
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Oresol
Absorption
Rapidly absorbed from the GI tract
Oresol
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Oresol
Patient Information
No information avaliable
Oresol
Organisms Affected
Humans and other mammals