Fenesin
Brand names,
Fenesin
Analogs
Fenesin
Brand Names Mixture
Fenesin
Chemical_Formula
C10H14O4
Fenesin
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Fenesin
fda sheet
Fenesin
msds (material safety sheet)
Fenesin
Synthesis Reference
No information avaliable
Fenesin
Molecular Weight
198.216 g/mol
Fenesin
Melting Point
78.5 oC
Fenesin
H2O Solubility
50 mg/mL
Fenesin
State
Solid
Fenesin
LogP
0.95
Fenesin
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Fenesin
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Fenesin
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Fenesin
Absorption
Rapidly absorbed from the GI tract
Fenesin
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Fenesin
Patient Information
No information avaliable
Fenesin
Organisms Affected
Humans and other mammals