Glyceryl guiacolate
Brand names,
Glyceryl guiacolate
Analogs
Glyceryl guiacolate
Brand Names Mixture
Glyceryl guiacolate
Chemical_Formula
C10H14O4
Glyceryl guiacolate
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Glyceryl guiacolate
fda sheet
Glyceryl guiacolate
msds (material safety sheet)
Glyceryl guiacolate
Synthesis Reference
No information avaliable
Glyceryl guiacolate
Molecular Weight
198.216 g/mol
Glyceryl guiacolate
Melting Point
78.5 oC
Glyceryl guiacolate
H2O Solubility
50 mg/mL
Glyceryl guiacolate
State
Solid
Glyceryl guiacolate
LogP
0.95
Glyceryl guiacolate
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Glyceryl guiacolate
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Glyceryl guiacolate
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Glyceryl guiacolate
Absorption
Rapidly absorbed from the GI tract
Glyceryl guiacolate
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Glyceryl guiacolate
Patient Information
No information avaliable
Glyceryl guiacolate
Organisms Affected
Humans and other mammals