Glyceryl guaicolate
Brand names,
Glyceryl guaicolate
Analogs
Glyceryl guaicolate
Brand Names Mixture
Glyceryl guaicolate
Chemical_Formula
C10H14O4
Glyceryl guaicolate
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Glyceryl guaicolate
fda sheet
Glyceryl guaicolate
msds (material safety sheet)
Glyceryl guaicolate
Synthesis Reference
No information avaliable
Glyceryl guaicolate
Molecular Weight
198.216 g/mol
Glyceryl guaicolate
Melting Point
78.5 oC
Glyceryl guaicolate
H2O Solubility
50 mg/mL
Glyceryl guaicolate
State
Solid
Glyceryl guaicolate
LogP
0.95
Glyceryl guaicolate
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Glyceryl guaicolate
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Glyceryl guaicolate
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Glyceryl guaicolate
Absorption
Rapidly absorbed from the GI tract
Glyceryl guaicolate
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Glyceryl guaicolate
Patient Information
No information avaliable
Glyceryl guaicolate
Organisms Affected
Humans and other mammals