Glycerin guaiacolate
Brand names,
Glycerin guaiacolate
Analogs
Glycerin guaiacolate
Brand Names Mixture
Glycerin guaiacolate
Chemical_Formula
C10H14O4
Glycerin guaiacolate
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Glycerin guaiacolate
fda sheet
Glycerin guaiacolate
msds (material safety sheet)
Glycerin guaiacolate
Synthesis Reference
No information avaliable
Glycerin guaiacolate
Molecular Weight
198.216 g/mol
Glycerin guaiacolate
Melting Point
78.5 oC
Glycerin guaiacolate
H2O Solubility
50 mg/mL
Glycerin guaiacolate
State
Solid
Glycerin guaiacolate
LogP
0.95
Glycerin guaiacolate
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Glycerin guaiacolate
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Glycerin guaiacolate
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Glycerin guaiacolate
Absorption
Rapidly absorbed from the GI tract
Glycerin guaiacolate
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Glycerin guaiacolate
Patient Information
No information avaliable
Glycerin guaiacolate
Organisms Affected
Humans and other mammals