Methphenoxydiol
Brand names,
Methphenoxydiol
Analogs
Methphenoxydiol
Brand Names Mixture
Methphenoxydiol
Chemical_Formula
C10H14O4
Methphenoxydiol
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Methphenoxydiol
fda sheet
Methphenoxydiol
msds (material safety sheet)
Methphenoxydiol
Synthesis Reference
No information avaliable
Methphenoxydiol
Molecular Weight
198.216 g/mol
Methphenoxydiol
Melting Point
78.5 oC
Methphenoxydiol
H2O Solubility
50 mg/mL
Methphenoxydiol
State
Solid
Methphenoxydiol
LogP
0.95
Methphenoxydiol
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Methphenoxydiol
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Methphenoxydiol
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Methphenoxydiol
Absorption
Rapidly absorbed from the GI tract
Methphenoxydiol
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Methphenoxydiol
Patient Information
No information avaliable
Methphenoxydiol
Organisms Affected
Humans and other mammals