Guaiacuran
Brand names,
Guaiacuran
Analogs
Guaiacuran
Brand Names Mixture
Guaiacuran
Chemical_Formula
C10H14O4
Guaiacuran
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaiacuran
fda sheet
Guaiacuran
msds (material safety sheet)
Guaiacuran
Synthesis Reference
No information avaliable
Guaiacuran
Molecular Weight
198.216 g/mol
Guaiacuran
Melting Point
78.5 oC
Guaiacuran
H2O Solubility
50 mg/mL
Guaiacuran
State
Solid
Guaiacuran
LogP
0.95
Guaiacuran
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaiacuran
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaiacuran
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaiacuran
Absorption
Rapidly absorbed from the GI tract
Guaiacuran
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guaiacuran
Patient Information
No information avaliable
Guaiacuran
Organisms Affected
Humans and other mammals