Guaia-rom
Brand names,
Guaia-rom
Analogs
Guaia-rom
Brand Names Mixture
Guaia-rom
Chemical_Formula
C10H14O4
Guaia-rom
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Guaia-rom
fda sheet
Guaia-rom
msds (material safety sheet)
Guaia-rom
Synthesis Reference
No information avaliable
Guaia-rom
Molecular Weight
198.216 g/mol
Guaia-rom
Melting Point
78.5 oC
Guaia-rom
H2O Solubility
50 mg/mL
Guaia-rom
State
Solid
Guaia-rom
LogP
0.95
Guaia-rom
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Guaia-rom
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Guaia-rom
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Guaia-rom
Absorption
Rapidly absorbed from the GI tract
Guaia-rom
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Guaia-rom
Patient Information
No information avaliable
Guaia-rom
Organisms Affected
Humans and other mammals