Glycero-guaiacol ether
Brand names,
Glycero-guaiacol ether
Analogs
Glycero-guaiacol ether
Brand Names Mixture
Glycero-guaiacol ether
Chemical_Formula
C10H14O4
Glycero-guaiacol ether
RX_link
http://www.rxlist.com/cgi/generic2/guaifen.htm
Glycero-guaiacol ether
fda sheet
Glycero-guaiacol ether
msds (material safety sheet)
Glycero-guaiacol ether
Synthesis Reference
No information avaliable
Glycero-guaiacol ether
Molecular Weight
198.216 g/mol
Glycero-guaiacol ether
Melting Point
78.5 oC
Glycero-guaiacol ether
H2O Solubility
50 mg/mL
Glycero-guaiacol ether
State
Solid
Glycero-guaiacol ether
LogP
0.95
Glycero-guaiacol ether
Dosage Forms
Liquid; Powder for solution; Syrup; Tablet
Glycero-guaiacol ether
Indication
Used to assist the expectoration of phlegm from the airways in acute respiratory tract infections.
Glycero-guaiacol ether
Pharmacology
Guaifenesin is an expectorant which increases the output of phlegm (sputum) and bronchial secretions by reducing adhesiveness and surface tension. The increased flow of less viscous secretions promotes ciliary action and changes a dry, unproductive cough to one that is more productive and less frequent. By reducing the viscosity and adhesiveness of secretions, guaifenesin increases the efficacy of the mucociliary mechanism in removing accumulated secretions from the upper and lower airway.
Glycero-guaiacol ether
Absorption
Rapidly absorbed from the GI tract
Glycero-guaiacol ether
side effects and Toxicity
LD50 1510 mg/kg (rat, oral)
Glycero-guaiacol ether
Patient Information
No information avaliable
Glycero-guaiacol ether
Organisms Affected
Humans and other mammals